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GHK-Cu (molecular weight approximately 340 Da as the copper complex) sits near the edge of the 500 Da rule used in dermal absorption research

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adjuvants such as piperine (Heidari et al., 2023), the use of liposomal curcumin (Li et al., 2005), the use of curcumin phospholipid complex (Mirzaei et al., 2017) and the use of structural analogues of curcumin (Rodrigues et al., 2021